A new generation of biomarker driven wearables is moving migraine care from reaction to prediction, giving users early signals before pain begins.

Migraine remains one of the most disabling neurological conditions globally, affecting over one billion people and disproportionately impacting women. Despite its prevalence, migraine care has largely remained reactive, focused on symptom management after pain begins rather than early intervention. Wearables have helped users track sleep, stress, and activity, but until now, they have lacked the ability to predict migraine risk windows in advance.
Ultrahuman is addressing this gap with the launch of Migraine PowerPlug, a global first feature that enables the Ultrahuman Ring AIR to predict migraine risk windows using biomarker analysis. Developed in partnership with Click Therapeutics, the feature is built on the technology behind Click’s FDA authorised digital migraine intervention. By combining sleep, heart rate variability, stress, and movement data, Migraine PowerPlug shifts the ring from a passive tracking device to an active, predictive health tool.
The feature integrates digital therapeutic principles into everyday wearable use, offering users real time insights and guided interventions designed to fit daily life. Instead of relying solely on occasional clinical visits, Migraine PowerPlug extends migraine management beyond the clinic by helping users identify personal triggers, anticipate high risk periods, and take preventive action before symptoms escalate. This approach is especially relevant for women, where hormonal changes often influence migraine patterns.
Key features of the technology include:
- First smart ring feature to predict migraine risk windows
- Built using FDA authorised digital therapeutic technology from Click Therapeutics
- Biomarker driven analysis of sleep, HRV, stress, and movement
- Personalized lifestyle guidance including sleep, hydration, and activity goals
- Designed for real time, daily migraine management
Mohit Kumar, CEO of Ultrahuman, says,“Helping people improve how they feel every day is core to Ultrahuman’s mission. By turning biometric insights into actionable guidance, we are enabling proactive migraine care.”






